Peptidyl-prolyl cis-trans isomerase FKBP1B (FKBP1B)

About Peptidyl-prolyl cis-trans isomerase FKBP1B

Peptidyl-prolyl cis-trans isomerase FKBP1B (FKBP1B) is a protein from Homo sapiens identified by UniProt accession P68106, 108 residues long. MolForge cross-references it against 0 known binders and 220 disease associations.

Target properties

Protein name	Peptidyl-prolyl cis-trans isomerase FKBP1B
UniProt accession	P68106
Gene	FKBP1B
Organism	Homo sapiens
Length	108 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Approved drugs hitting this target (3)

DrugCentral-linked approved drugs that act on this protein.

Disease associations (220)

Diseases linked to this target (Open Targets).

familial atrial fibrillation · score 0.11
lifestyle measurement · score 0.11
MODY · score 0.10
Brugada syndrome · score 0.09
Familial short QT syndrome · score 0.09
atrial fibrillation · score 0.09
Romano-Ward syndrome · score 0.09
hypertrophic cardiomyopathy · score 0.08
atrial fibrillation, familial, 12 · score 0.08
atrial fibrillation, familial, 8 · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P68106-F1	alphafold	PREDICTED	94.89	—

Amino-acid sequence (108 residues)

MGVEIETISP GDGRTFPKKG QTCVVHYTGM LQNGKKFDSS RDRNKPFKFR IGKQEVIKGF EEGAAQMSLG QRAKLTCTPD VAYGATGHPG VIPPNATLIF DVELLNLE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards