About UBX domain-containing protein 2A
UBX domain-containing protein 2A (UBXN2A) is a protein
from Homo sapiens identified by UniProt accession
P68543, 259 residues long.
MolForge cross-references it against 0 known binders and
99 disease associations.
Target properties
| Protein name | UBX domain-containing protein 2A |
|---|
| UniProt accession | P68543 |
|---|
| Gene | UBXN2A |
|---|
| Organism | Homo sapiens |
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| Length | 259 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (99)
Diseases linked to this target (Open Targets).
- mean corpuscular volume · score 0.32
- platelet crit · score 0.29
- platelet count · score 0.28
- mean reticulocyte volume · score 0.26
- reticulocyte count · score 0.26
- vital capacity · score 0.25
- lymphocyte count · score 0.24
- mean corpuscular hemoglobin concentration · score 0.24
- Red cell distribution width · score 0.24
- lymphocyte percentage of leukocytes · score 0.24
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P68543-F1 | alphafold | PREDICTED | 73.36 | — |
Amino-acid sequence (259 residues)
MKDVDNLKSI KEEWVCETGS DNQPLGNNQQ SNCEYFVDSL FEEAQKVSSK CVSPAEQKKQ VDVNIKLWKN GFTVNDDFRS YSDGASQQFL NSIKKGELPS ELQGIFDKEE VDVKVEDKKN EICLSTKPVF QPFSGQGHRL GSATPKIVSK AKNIEVENKN NLSAVPLNNL EPITNIQIWL ANGKRIVQKF NITHRVSHIK DFIEKYQGSQ RSPPFSLATA LPVLRLLDET LTLEEADLQN AVIIQRLQKT ASFRELSEH
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