About Protein FAM193A
Protein FAM193A (FAM193A) is a protein
from Homo sapiens identified by UniProt accession
P78312, 1515 residues long.
MolForge cross-references it against 0 known binders and
69 disease associations.
Target properties
| Protein name | Protein FAM193A |
|---|
| UniProt accession | P78312 |
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| Gene | FAM193A |
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| Organism | Homo sapiens |
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| Length | 1515 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
|---|
Disease associations (69)
Diseases linked to this target (Open Targets).
- systolic blood pressure · score 0.24
- eosinophil count · score 0.19
- pulse pressure measurement · score 0.18
- hypertension · score 0.17
- systemic lupus erythematosus · score 0.15
- blood pressure · score 0.15
- cognitive function measurement · score 0.13
- self reported educational attainment · score 0.12
- chronotype measurement · score 0.11
- eosinophil percentage of leukocytes · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P78312-F1 | alphafold | PREDICTED | 50.06 | — |
Amino-acid sequence (1515 residues)
MSPADAKRGA KRRKNKRGGG GGSGGGNGGA SSGKAGPAAA LRGSQAAGLA APGSAAGLVG GAAAANGPLG AGASAGGAAP GGYFETPFSF GMNHRTPPYP AGDYCLLCRS ERKDSSFLES GIKTASKLAL SMAPKGNSVL HLPLWVCPDC RRTVEKEERH GGLDQPVSQD FLLHSSLGGS QPEAGSGGRL ALGAQTLPSD TACSCEACSE RREISAEADR EPQQLQNYWS EVRYTVRCIY RQAGTPLADD QDQSLVPDKE GVKELVDRLC ERDPYQLYQR LEQQAREYVL EMKVRLLRQL SAAAKVKAPS GLQGPPQAHQ FISLLLEEYG ALCQAARSIS TFLGTLENEH LKKFQVTWEL HNKHLFENLV FSEPLLQSNL PALVSQIRLG TTTHDTCSED TYSTLLQRYQ RSEEELRRVA EEWLECQKRI DAYVDEQMTM KTKQRMLTED WELFKQRRFI EEQLTNKKAV TGENNFTDTM RHMLSSRLSM PDCPNCNYRR RCACDDCSLS HILTCGIMDP PVTDDIHIHQ LPLQVDPAPD YLAERSPPSV SSASSGSGSS SPITIQQHPR LILTDSGSAP TFCSDDEDVA PLSAKFADIY PLSNYDDTEV VANMNGIHSE LNGGGENMAL KDESPQISST SSSSSEADDE EADGESSGEP PGAPKEDGVL GSRSPRTEES KADSPPPSYP TQQAEQAPNT CECHVCKQEA SGLTPSAMTA GALPPGHQFL SPEKPTHPAL HLYPHIHGHV PLHTVPHLPR PLIHPTLYAT PPFTHSKALP PAPVQNHTNK HQVFNASLQD HIYPSCFGNT PEWNSSKFIS LWGSEVMNDK NWNPGTFLPD TISGSEILGP TLSETRPEAL PPPSSNETPA VSDSKEKKNA AKKKCLYNFQ DAFMEANKVV MATSSATSSV SCTATTVQSS NSQFRVSSKR PPSVGDVFHG ISKEDHRHSA PAAPRNSPTG LAPLPALSPA ALSPAALSPA STPHLANLAA PSFPKTATTT PGFVDTRKSF CPAPLPPATD GSISAPPSVC SDPDCEGHRC ENGVYDPQQD DGDESADEDS CSEHSSSTST STNQKEGKYC DCCYCEFFGH GGPPAAPTSR NYAEMREKLR LRLTKRKEEQ PKKMDQISER ESVVDHRRVE DLLQFINSSE TKPVSSTRAA KRARHKQRKL EEKARLEAEA RAREHLHLQE EQRRREEEED EEEEEDRFKE EFQRLQELQK LRAVKKKKKE RPSKDCPKLD MLTRNFQAAT ESVPNSGNIH NGSLEQTEEP ETSSHSPSRH MNHSEPRPGL GADGDAADPV DTRDSKFLLP KEVNGKQHEP LSFFFDIMQH HKEGNGKQKL RQTSKASSEP ARRPTEPPKA TEGQSKPRAQ TESKAKVVDL MSITEQKREE RKVNSNNNNK KQLNHIKDEK SNPTPMEPTS PGEHQQNSKL VLAESPQPKG KNKKNKKKKG DRVNNSIDDV FLPKDIDLDS VDMDETEREV EYFKRFCLDS ARQTRQRLSI NWSNFSLKKA TFAAH
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