About Cytochrome P450 4F2
Cytochrome P450 4F2 (CYP4F2) is a protein
from Homo sapiens identified by UniProt accession
P78329, 520 residues long.
MolForge cross-references it against 0 known binders and
234 disease associations.
Target properties
| Protein name | Cytochrome P450 4F2 |
|---|
| UniProt accession | P78329 |
|---|
| Gene | CYP4F2 |
|---|
| Organism | Homo sapiens |
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| Length | 520 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (234)
Diseases linked to this target (Open Targets).
- serum metabolite measurement · score 0.43
- urinary metabolite measurement · score 0.41
- heel bone mineral density · score 0.39
- response to anticoagulant · score 0.37
- cholesterol embolism · score 0.36
- serum alanine aminotransferase measurement · score 0.33
- phosphatidylethanolamine measurement · score 0.30
- aspartate aminotransferase measurement · score 0.29
- metabolite measurement · score 0.29
- PHF-tau measurement · score 0.28
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P78329-F1 | alphafold | PREDICTED | 91.79 | — |
Amino-acid sequence (520 residues)
MSQLSLSWLG LWPVAASPWL LLLLVGASWL LAHVLAWTYA FYDNCRRLRC FPQPPRRNWF WGHQGMVNPT EEGMRVLTQL VATYPQGFKV WMGPISPLLS LCHPDIIRSV INASAAIAPK DKFFYSFLEP WLGDGLLLSA GDKWSRHRRM LTPAFHFNIL KPYMKIFNES VNIMHAKWQL LASEGSACLD MFEHISLMTL DSLQKCVFSF DSHCQEKPSE YIAAILELSA LVSKRHHEIL LHIDFLYYLT PDGQRFRRAC RLVHDFTDAV IQERRRTLPS QGVDDFLQAK AKSKTLDFID VLLLSKDEDG KKLSDEDIRA EADTFMFEGH DTTASGLSWV LYHLAKHPEY QERCRQEVQE LLKDREPKEI EWDDLAHLPF LTMCMKESLR LHPPVPVISR HVTQDIVLPD GRVIPKGIIC LISVFGTHHN PAVWPDPEVY DPFRFDPENI KERSPLAFIP FSAGPRNCIG QTFAMAEMKV VLALTLLRFR VLPDHTEPRR KPELVLRAEG GLWLRVEPLS
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