About Ribonuclease P protein subunit p38
Ribonuclease P protein subunit p38 (RPP38) is a protein
from Homo sapiens identified by UniProt accession
P78345, 283 residues long.
MolForge cross-references it against 0 known binders and
11 disease associations.
Target properties
| Protein name | Ribonuclease P protein subunit p38 |
|---|
| UniProt accession | P78345 |
|---|
| Gene | RPP38 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 283 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (11)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.30
- protein measurement · score 0.11
- body height · score 0.04
- systemic scleroderma · score 0.02
- neoplasm · score 0.00
- calf circumference measurement · score 0.00
- major depressive disorder · score 0.00
- cancer · score 0.00
- non-small cell lung carcinoma · score 0.00
- human papilloma virus infection · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P78345-F1 | alphafold | PREDICTED | 72.76 | — |
Amino-acid sequence (283 residues)
MAAAPQAPGR GSLRKTRPLV VKTSLNNPYI IRWSALESED MHFILQTLED RLKAIGLQKI EDKKKKNKTP FLKKESREKC SIAVDISENL KEKKTDAKQQ VSGWTPAHVR KQLAIGVNEV TRALERRELL LVLVCKSVKP AMITSHLIQL SLSRSVPACQ VPRLSERIAP VIGLKCVLAL AFKKNTTDFV DEVRAIIPRV PSLSVPWLQD RIEDSGENLE TEPLESQDRE LLDTSFEDLS KPKRKLADGR QASVTLQPLK IKKLIPNPNK IRKPPKSKKA TPK
Explore Ribonuclease P protein subunit p38 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets