About Ribonuclease P protein subunit p30
Ribonuclease P protein subunit p30 (RPP30) is a protein
from Homo sapiens identified by UniProt accession
P78346, 268 residues long.
MolForge cross-references it against 0 known binders and
41 disease associations.
Target properties
| Protein name | Ribonuclease P protein subunit p30 |
|---|
| UniProt accession | P78346 |
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| Gene | RPP30 |
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| Organism | Homo sapiens |
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| Length | 268 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (41)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.51
- intraocular pressure measurement · score 0.15
- white matter microstructure measurement · score 0.11
- glioblastoma multiforme · score 0.08
- neoplasm · score 0.07
- hemoglobin measurement · score 0.07
- refractive error measurement · score 0.06
- gonorrhea · score 0.06
- protein measurement · score 0.06
- electrocardiography · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P78346-F1 | alphafold | PREDICTED | 84.83 | — |
Amino-acid sequence (268 residues)
MAVFADLDLR AGSDLKALRG LVETAAHLGY SVVAINHIVD FKEKKQEIEK PVAVSELFTT LPIVQGKSRP IKILTRLTII VSDPSHCNVL RATSSRARLY DVVAVFPKTE KLFHIACTHL DVDLVCITVT EKLPFYFKRP PINVAIDRGL AFELVYSPAI KDSTMRRYTI SSALNLMQIC KGKNVIISSA AERPLEIRGP YDVANLGLLF GLSESDAKAA VSTNCRAALL HGETRKTAFG IISTVKKPRP SEGDEDCLPA SKKAKCEG
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