About Claudin-10
Claudin-10 (CLDN10) is a protein
from Homo sapiens identified by UniProt accession
P78369, 228 residues long.
MolForge cross-references it against 0 known binders and
147 disease associations.
Target properties
| Protein name | Claudin-10 |
|---|
| UniProt accession | P78369 |
|---|
| Gene | CLDN10 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 228 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (147)
Diseases linked to this target (Open Targets).
- cystatin C measurement · score 0.71
- helix rolling · score 0.62
- creatinine measurement · score 0.56
- serum urea measurement · score 0.52
- urate measurement · score 0.47
- urea measurement · score 0.34
- erythrocyte count · score 0.32
- uric acid measurement · score 0.31
- hematocrit · score 0.29
- urolithiasis · score 0.27
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P78369-F1 | alphafold | PREDICTED | 80.10 | — |
Amino-acid sequence (228 residues)
MASTASEIIA FMVSISGWVL VSSTLPTDYW KVSTIDGTVI TTATYWANLW KACVTDSTGV SNCKDFPSML ALDGYIQACR GLMIAAVSLG FFGSIFALFG MKCTKVGGSD KAKAKIACLA GIVFILSGLC SMTGCSLYAN KITTEFFDPL FVEQKYELGA ALFIGWAGAS LCIIGGVIFC FSISDNNKTP RYTYNGATSV MSSRTKYHGG EDFKTTNPSK QFDKNAYV
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