About Solute carrier family 35 member B1
Solute carrier family 35 member B1 (SLC35B1) is a protein
from Homo sapiens identified by UniProt accession
P78383, 322 residues long.
MolForge cross-references it against 0 known binders and
16 disease associations.
Target properties
| Protein name | Solute carrier family 35 member B1 |
|---|
| UniProt accession | P78383 |
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| Gene | SLC35B1 |
|---|
| Organism | Homo sapiens |
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| Length | 322 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (16)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.42
- mean reticulocyte volume · score 0.30
- cardiovascular disease · score 0.28
- pulse pressure measurement · score 0.21
- mosaic loss of chromosome Y measurement · score 0.13
- serum albumin measurement · score 0.08
- total blood protein measurement · score 0.07
- calcium measurement · score 0.05
- platelet count · score 0.04
- Alzheimer disease · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P78383-F1 | alphafold | PREDICTED | 86.42 | — |
Amino-acid sequence (322 residues)
MASSSSLVPD RLRLPLCFLG VFVCYFYYGI LQEKITRGKY GEGAKQETFT FALTLVFIQC VINAVFAKIL IQFFDTARVD RTRSWLYAAC SISYLGAMVS SNSALQFVNY PTQVLGKSCK PIPVMLLGVT LLKKKYPLAK YLCVLLIVAG VALFMYKPKK VVGIEEHTVG YGELLLLLSL TLDGLTGVSQ DHMRAHYQTG SNHMMLNINL WSTLLLGMGI LFTGELWEFL SFAERYPAII YNILLFGLTS ALGQSFIFMT VVYFGPLTCS IITTTRKFFT ILASVILFAN PISPMQWVGT VLVFLGLGLD AKFGKGAKKT SH
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