Cyclin-A1 (CCNA1)

Homo sapiens — UniProt P78396

Gene: CCNA1Homo sapiensSwissProt reviewed

About Cyclin-A1

Cyclin-A1 (CCNA1) is a protein from Homo sapiens identified by UniProt accession P78396, 465 residues long. MolForge cross-references it against 0 known binders and 217 disease associations.

Target properties

Protein nameCyclin-A1
UniProt accessionP78396
GeneCCNA1
OrganismHomo sapiens
Length465 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-P78396-F1alphafoldPREDICTED67.60—

Amino-acid sequence (465 residues)

METGFPAIMY PGSFIGGWGE EYLSWEGPGL PDFVFQQQPV ESEAMHCSNP KSGVVLATVA RGPDACQILT RAPLGQDPPQ RTVLGLLTAN GQYRRTCGQG ITRIRCYSGS ENAFPPAGKK ALPDCGVQEP PKQGFDIYMD ELEQGDRDSC SVREGMAFED VYEVDTGTLK SDLHFLLDFN TVSPMLVDSS LLSQSEDISS LGTDVINVTE YAEEIYQYLR EAEIRHRPKA HYMKKQPDIT EGMRTILVDW LVEVGEEYKL RAETLYLAVN FLDRFLSCMS VLRGKLQLVG TAAMLLASKY EEIYPPEVDE FVYITDDTYT KRQLLKMEHL LLKVLAFDLT VPTTNQFLLQ YLRRQGVCVR TENLAKYVAE LSLLEADPFL KYLPSLIAAA AFCLANYTVN KHFWPETLAA FTGYSLSEIV PCLSELHKAY LDIPHRPQQA IREKYKASKY LCVSLMEPPA VLLLQ

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Quick facts

UniProtP78396
GeneCCNA1
OrganismHomo sapiens
Length465
Binders0
Diseases217
View on UniProt