About Glutathione S-transferase omega-1
Glutathione S-transferase omega-1 (GSTO1) is a protein
from Homo sapiens identified by UniProt accession
P78417, 241 residues long.
MolForge cross-references it against 0 known binders and
165 disease associations.
Target properties
| Protein name | Glutathione S-transferase omega-1 |
|---|
| UniProt accession | P78417 |
|---|
| Gene | GSTO1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 241 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Approved drugs hitting this target (4)
DrugCentral-linked approved drugs that act on this protein.
Disease associations (165)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.43
- Parkinson disease · score 0.30
- Alzheimer disease · score 0.30
- multiple sclerosis · score 0.29
- lysosomal storage disease · score 0.29
- blood protein measurement · score 0.29
- mathematical ability · score 0.27
- protein measurement · score 0.20
- chronic obstructive pulmonary disease · score 0.08
- non-small cell lung carcinoma · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P78417-F1 | alphafold | PREDICTED | 95.26 | — |
Amino-acid sequence (241 residues)
MSGESARSLG KGSAPPGPVP EGSIRIYSMR FCPFAERTRL VLKAKGIRHE VININLKNKP EWFFKKNPFG LVPVLENSQG QLIYESAITC EYLDEAYPGK KLLPDDPYEK ACQKMILELF SKVPSLVGSF IRSQNKEDYA GLKEEFRKEF TKLEEVLTNK KTTFFGGNSI SMIDYLIWPW FERLEAMKLN ECVDHTPKLK LWMAAMKEDP TVSALLTSEK DWQGFLELYL QNSPEACDYG L
Explore Glutathione S-transferase omega-1 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets