About Protein BTG2
Protein BTG2 (BTG2) is a protein
from Homo sapiens identified by UniProt accession
P78543, 158 residues long.
MolForge cross-references it against 0 known binders and
269 disease associations.
Target properties
| Protein name | Protein BTG2 |
|---|
| UniProt accession | P78543 |
|---|
| Gene | BTG2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 158 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (269)
Diseases linked to this target (Open Targets).
- mean reticulocyte volume · score 0.41
- diffuse large B-cell lymphoma · score 0.38
- mean corpuscular hemoglobin concentration · score 0.37
- mean corpuscular volume · score 0.36
- Immature Reticulocyte Fraction Measurement · score 0.32
- Red cell distribution width · score 0.31
- erythrocyte count · score 0.30
- lung adenocarcinoma · score 0.29
- mean corpuscular hemoglobin · score 0.29
- reticulocyte count · score 0.28
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P78543-F1 | alphafold | PREDICTED | 85.25 | — |
Amino-acid sequence (158 residues)
MSHGKGTDML PEIAAAVGFL SSLLRTRGCV SEQRLKVFSG ALQEALTEHY KHHWFPEKPS KGSGYRCIRI NHKMDPIISR VASQIGLSQP QLHQLLPSEL TLWVDPYEVS YRIGEDGSIC VLYEEAPLAA SCGLLTCKNQ VLLGRSSPSK NYVMAVSS
Explore Protein BTG2 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets