ETS-related transcription factor Elf-3 (ELF3)

About ETS-related transcription factor Elf-3

ETS-related transcription factor Elf-3 (ELF3) is a protein from Homo sapiens identified by UniProt accession P78545, 371 residues long. MolForge cross-references it against 0 known binders and 337 disease associations.

Target properties

Protein name	ETS-related transcription factor Elf-3
UniProt accession	P78545
Gene	ELF3
Organism	Homo sapiens
Length	371 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (337)

Diseases linked to this target (Open Targets).

urinary bladder cancer · score 0.48
cholangiocarcinoma · score 0.31
systemic lupus erythematosus · score 0.27
blood protein measurement · score 0.26
creatinine measurement · score 0.24
cystatin C measurement · score 0.24
matrix metalloproteinase 7 measurement · score 0.24
colorectal adenocarcinoma · score 0.23
lung adenocarcinoma · score 0.21
hepatocellular carcinoma · score 0.21

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P78545-F1	alphafold	PREDICTED	64.75	—

Amino-acid sequence (371 residues)

MAATCEISNI FSNYFSAMYS SEDSTLASVP PAATFGADDL VLTLSNPQMS LEGTEKASWL GEQPQFWSKT QVLDWISYQV EKNKYDASAI DFSRCDMDGA TLCNCALEEL RLVFGPLGDQ LHAQLRDLTS SSSDELSWII ELLEKDGMAF QEALDPGPFD QGSPFAQELL DDGQQASPYH PGSCGAGAPS PGSSDVSTAG TGASRSSHSS DSGGSDVDLD PTDGKLFPSD GFRDCKKGDP KHGKRKRGRP RKLSKEYWDC LEGKKSKHAP RGTHLWEFIR DILIHPELNE GLMKWENRHE GVFKFLRSEA VAQLWGQKKK NSNMTYEKLS RAMRYYYKRE ILERVDGRRL VYKFGKNSSG WKEEEVLQSR N

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards