C-C motif chemokine 20 (CCL20)

About C-C motif chemokine 20

C-C motif chemokine 20 (CCL20) is a protein from Homo sapiens identified by UniProt accession P78556, 96 residues long. MolForge cross-references it against 0 known binders and 578 disease associations.

Target properties

Protein name	C-C motif chemokine 20
UniProt accession	P78556
Gene	CCL20
Organism	Homo sapiens
Length	96 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (578)

Diseases linked to this target (Open Targets).

ulcerative colitis · score 0.32
asthma · score 0.29
childhood onset asthma · score 0.29
allergic disease · score 0.26
age at onset · score 0.26
acute myeloid leukemia · score 0.24
inflammatory bowel disease · score 0.24
psoriasis · score 0.22
C-C motif chemokine 20 measurement · score 0.21
ankylosing spondylitis · score 0.20

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P78556-F1	alphafold	PREDICTED	88.70	—

Amino-acid sequence (96 residues)

MCCTKSLLLA ALMSVLLLHL CGESEAASNF DCCLGYTDRI LHPKFIVGFT RQLANEGCDI NAIIFHTKKK LSVCANPKQT WVKYIVRLLS KKVKNM

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards