About Microtubule-associated protein 1A
Microtubule-associated protein 1A (MAP1A) is a protein
from Homo sapiens identified by UniProt accession
P78559, 2803 residues long.
MolForge cross-references it against 0 known binders and
165 disease associations.
Target properties
| Protein name | Microtubule-associated protein 1A |
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| UniProt accession | P78559 |
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| Gene | MAP1A |
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| Organism | Homo sapiens |
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| Length | 2803 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (165)
Diseases linked to this target (Open Targets).
- mean corpuscular volume · score 0.39
- sex hormone-binding globulin measurement · score 0.39
- hemoglobin measurement · score 0.39
- platelet count · score 0.37
- lymphocyte count · score 0.35
- mean corpuscular hemoglobin concentration · score 0.34
- Neurodevelopmental disorder · score 0.34
- Red cell distribution width · score 0.33
- hematocrit · score 0.32
- diastolic blood pressure · score 0.30
3D Structure (9)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
Amino-acid sequence (2803 residues)
MDGVAEFSEY VSETVDVPSP FDLLEPPTSG GFLKLSKPCC YIFPGGRGDS ALFAVNGFNI LVDGGSDRKS CFWKLVRHLD RIDSVLLTHI GADNLPGING LLQRKVAELE EEQSQGSSSY SDWVKNLISP ELGVVFFNVP EKLRLPDASR KAKRSIEEAC LTLQHLNRLG IQAEPLYRVV SNTIEPLTLF HKMGVGRLDM YVLNPVKDSK EMQFLMQKWA GNSKAKTGIV LPNGKEAEIS VPYLTSITAL VVWLPANPTE KIVRVLFPGN APQNKILEGL EKLRHLDFLR YPVATQKDLA SGAVPTNLKP SKIKQRADSK ESLKATTKTA VSKLAKREEV VEEGAKEARS ELAKELAKTE KKAKESSEKP PEKPAKPERV KTESSEALKA EKRKLIKDKV GKKHLKEKIS KLEEKKDKEK KEIKKERKEL KKDEGRKEEK KDAKKEEKRK DTKPELKKIS KPDLKPFTPE VRKTLYKAKV PGRVKIDRSR AIRGEKELSS EPQTPPAQKG TVPLPTISGH RELVLSSPED LTQDFEEMKR EERALLAEQR DTGLGDKPFP LDTAEEGPPS TAIQGTPPSV PGLGQEEHVM KEKELVPEVP EEQGSKDRGL DSGAETEEEK DTWEEKKQRE AERLPDRTEA REESEPEVKE DVIEKAELEE MEEVHPSDEE EEDATKAEGF YQKHMQEPLK VTPRSREAFG GRELGLQGKA PEKETSLFLS SLTTPAGATE HVSYIQDETI PGYSETEQTI SDEEIHDEPE ERPAPPRFHT STYDLPGPEG AGPFEASQPA DSAVPATSGK VYGTPETELT YPTNIVAAPL AEEEHVSSAT SITECDKLSS FATSVAEDQS VASLTAPQTE ETGKSSLLLD TVTSIPSSRT EATQGLDYVP SAGTISPTSS LEEDKGFKSP PCEDFSVTGE SEKRGEIIGK GLSGERAVEE EEEETANVEM SEKLCSQYGT PVFSAPGHAL HPGEPALGEA EERCLSPDDS TVKMASPPPS GPPSATHTPF HQSPVEEKSE PQDFQEADSW GDTKRTPGVG KEDAAEETVK PGPEEGTLEK EEKVPPPRSP QAQEAPVNID EGLTGCTIQL LPAQDKAIVF EIMEAGEPTG PILGAEALPG GLRTLPQEPG KPQKDEVLRY PDRSLSPEDA ESLSVLSVPS PDTANQEPTP KSPCGLTEQY LHKDRWPEVS PEDTQSLSLS EESPSKETSL DVSSKQLSPE SLGTLQFGEL NLGKEEMGHL MQAEDTSHHT APMSVPEPHA ATASPPTDGT TRYSAQTDIT DDSLDRKSPA SSFSHSTPSG NGKYLPGAIT SPDEHILTPD SSFSKSPESL PGPALEDIAI KWEDKVPGLK DRTSEQKKEP EPKDEVLQQK DKTLEHKEVV EPKDTAIYQK DEALHVKNEA VKQQDKALEQ KGRDLEQKDT ALEQKDKALE PKDKDLEEKD KALEQKDKIP EEKDKALEQK DTALEQKDKA LEPKDKDLEQ KDRVLEQKEK IPEEKDKALD QKVRSVEHKA PEDTVAEMKD RDLEQTDKAP EQKHQAQEQK DKVSEKKDQA LEQKYWALGQ KDEALEQNIQ ALEENHQTQE QESLVQEDKT RKPKMLEEKS PEKVKAMEEK LEALLEKTKA LGLEESLVQE GRAREQEEKY WRGQDVVQEW QETSPTREEP AGEQKELAPA WEDTSPEQDN RYWRGREDVA LEQDTYWREL SCERKVWFPH ELDGQGARPH YTEERESTFL DEGPDDEQEV PLREHATRSP WASDFKDFQE SSPQKGLEVE RWLAESPVGL PPEEEDKLTR SPFEIISPPA SPPEMVGQRV PSAPGQESPI PDPKLMPHMK NEPTTPSWLA DIPPWVPKDR PLPPAPLSPA PGPPTPAPES HTPAPFSWGT AEYDSVVAAV QEGAAELEGG PYSPLGKDYR KAEGEREEEG RAEAPDKSSH SSKVPEASKS HATTEPEQTE PEQREPTPYP DERSFQYADI YEQMMLTGLG PACPTREPPL GAAGDWPPCL STKEAAAGRN TSAEKELSSP ISPKSLQSDT PTFSYAALAG PTVPPRPEPG PSMEPSLTPP AVPPRAPILS KGPSPPLNGN ILSCSPDRRS PSPKESGRSH WDDSTSDSEL EKGAREQPEK EAQSPSPPHP IPMGSPTLWP ETEAHVSPPL DSHLGPARPS LDFPASAFGF SSLQPAPPQL PSPAEPRSAP CGSLAFSGDR ALALAPGPPT RTRHDEYLEV TKAPSLDSSL PQLPSPSSPG APLLSNLPRP ASPALSEGSS SEATTPVISS VAERFSPSLE AAEQESGELD PGMEPAAHSL WDLTPLSPAP PASLDLALAP APSLPGDMGD GILPCHLECS EAATEKPSPF QVPSEDCAAN GPTETSPNPP GPAPAKAENE EAAACPAWER GAWPEGAERS SRPDTLLSPE QPVCPAGGSG GPPSSASPEV EAGPQGCATE PRPHRGELSP SFLNPPLPPS IDDRDLSTEE VRLVGRGGRR RVGGPGTTGG PCPVTDETPP TSASDSGSSQ SDSDVPPETE ECPSITAEAA LDSDEDGDFL PVDKAGGVSG THHPRPGHDP PPLPQPDPRP SPPRPDVCMA DPEGLSSESG RVERLREKEK VQGRVGRRAP GKAKPASPAR RLDLRGKRSP TPGKGPADRA SRAPPRPRST TSQVTPAEEK DGHSPMSKGL VNGLKAGPMA LSSKGSSGAP VYVDLAYIPN HCSGKTADLD FFRRVRASYY VVSGNDPANG EPSRAVLDAL LEGKAQWGEN LQVTLIPTHD TEVTREWYQQ THEQQQQLNV LVLASSSTVV MQDESFPACK IEF
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