Proline-rich protein 3 (PRR3)

About Proline-rich protein 3

Proline-rich protein 3 (PRR3) is a protein from Homo sapiens identified by UniProt accession P79522, 188 residues long. MolForge cross-references it against 0 known binders and 9 disease associations.

Target properties

Protein name	Proline-rich protein 3
UniProt accession	P79522
Gene	PRR3
Organism	Homo sapiens
Length	188 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (9)

Diseases linked to this target (Open Targets).

influenza A (H1N1) · score 0.11
lymphocyte count · score 0.04
platelet-to-lymphocyte ratio · score 0.04
self reported educational attainment · score 0.03
serum IgM measurement · score 0.03
mucocutaneous lymph node syndrome · score 0.02
Graves disease · score 0.02
hemoglobin measurement · score 0.02
Alzheimer disease · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P79522-F1	alphafold	PREDICTED	60.70	—

Amino-acid sequence (188 residues)

MPKRKKQNHH QPPTQQQPPL PEREETGDEE DGSPIGPPSL LGPPPMANGK PGDPKSALHR GPPGSRGPLI PPLLSLPPPP WGRGPIRRGL GPRSSPYGRG WWGVNAEPPF PGPGHGGPTR GSFHKEQRNP RRLKSWSLIK NTCPPKDDPQ VMEDKSDRPV CRHFAKKGHC RYEDLCAFYH PGVNGPPL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards