About Interferon-induced 35 kDa protein
Interferon-induced 35 kDa protein (IFI35) is a protein
from Homo sapiens identified by UniProt accession
P80217, 286 residues long.
MolForge cross-references it against 0 known binders and
88 disease associations.
Target properties
| Protein name | Interferon-induced 35 kDa protein |
|---|
| UniProt accession | P80217 |
|---|
| Gene | IFI35 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 286 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (88)
Diseases linked to this target (Open Targets).
- total blood protein measurement · score 0.13
- neoplasm · score 0.10
- triple-negative breast cancer · score 0.08
- infection · score 0.06
- infect · score 0.06
- influenza · score 0.06
- renal cell carcinoma · score 0.05
- COVID-19 · score 0.05
- body mass index · score 0.04
- creatinine measurement · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P80217-F1 | alphafold | PREDICTED | 83.20 | — |
Amino-acid sequence (286 residues)
MSAPLDAALH ALQEEQARLK MRLWDLQQLR KELGDSPKDK VPFSVPKIPL VFRGHTQQDP EVPKSLVSNL RIHCPLLAGS ALITFDDPKV AEQVLQQKEH TINMEECRLR VQVQPLELPM VTTIQMSSQL SGRRVLVTGF PASLRLSEEE LLDKLEIFFG KTRNGGGDVD VRELLPGSVM LGFARDGVAQ RLCQIGQFTV PLGGQQVPLR VSPYVNGEIQ KAEIRSQPVP RSVLVLNIPD ILDGPELHDV LEIHFQKPTR GGGEVEALTV VPQGQQGLAV FTSESG
Explore Interferon-induced 35 kDa protein with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets