Metallothionein-1H (MT1H)

About Metallothionein-1H

Metallothionein-1H (MT1H) is a protein from Homo sapiens identified by UniProt accession P80294, 61 residues long. MolForge cross-references it against 0 known binders and 85 disease associations.

Target properties

Protein name	Metallothionein-1H
UniProt accession	P80294
Gene	MT1H
Organism	Homo sapiens
Length	61 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (85)

Diseases linked to this target (Open Targets).

hepatocellular carcinoma · score 0.10
Down syndrome · score 0.05
neoplasm · score 0.04
clear cell renal carcinoma · score 0.03
esophageal squamous cell carcinoma · score 0.02
Kidney Oncocytoma · score 0.02
ulcerative colitis · score 0.02
colorectal cancer · score 0.02
lung carcinoma · score 0.01
gastric cardia carcinoma · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P80294-F1	alphafold	PREDICTED	78.96	—

Amino-acid sequence (61 residues)

MDPNCSCEAG GSCACAGSCK CKKCKCTSCK KSCCSCCPLG CAKCAQGCIC KGASEKCSCC A

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards