Metallothionein-1X (MT1X)

About Metallothionein-1X

Metallothionein-1X (MT1X) is a protein from Homo sapiens identified by UniProt accession P80297, 61 residues long. MolForge cross-references it against 0 known binders and 110 disease associations.

Target properties

Protein name	Metallothionein-1X
UniProt accession	P80297
Gene	MT1X
Organism	Homo sapiens
Length	61 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (110)

Diseases linked to this target (Open Targets).

apolipoprotein A 1 measurement · score 0.10
hepatocellular carcinoma · score 0.10
nonpapillary renal cell carcinoma · score 0.08
neoplasm · score 0.07
acute myeloid leukemia · score 0.07
breast carcinoma · score 0.03
cancer · score 0.03
esophageal squamous cell carcinoma · score 0.03
ulcerative colitis · score 0.02
clear cell renal carcinoma · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P80297-F1	alphafold	PREDICTED	79.99	—

Amino-acid sequence (61 residues)

MDPNCSCSPV GSCACAGSCK CKECKCTSCK KSCCSCCPVG CAKCAQGCIC KGTSDKCSCC A

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards