Protein S100-A12 (S100A12)

About Protein S100-A12

Protein S100-A12 (S100A12) is a protein from Homo sapiens identified by UniProt accession P80511, 92 residues long. MolForge cross-references it against 0 known binders and 395 disease associations.

Target properties

Protein name	Protein S100-A12
UniProt accession	P80511
Gene	S100A12
Organism	Homo sapiens
Length	92 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (395)

Diseases linked to this target (Open Targets).

monocyte count · score 0.20
monocyte percentage of leukocytes · score 0.19
endometrial cancer · score 0.18
neutrophil count · score 0.18
multiple sclerosis · score 0.17
lysosomal storage disease · score 0.17
Alzheimer disease · score 0.17
neurodegenerative disease · score 0.17
Parkinson disease · score 0.17
neutrophil percentage of leukocytes · score 0.14

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P80511-F1	alphafold	PREDICTED	90.48	—

Amino-acid sequence (92 residues)

MTKLEEHLEG IVNIFHQYSV RKGHFDTLSK GELKQLLTKE LANTIKNIKD KAVIDEIFQG LDANQDEQVD FQEFISLVAI ALKAAHYHTH KE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards