About Brain acid soluble protein 1
Brain acid soluble protein 1 (BASP1) is a protein
from Homo sapiens identified by UniProt accession
P80723, 227 residues long.
MolForge cross-references it against 0 known binders and
126 disease associations.
Target properties
| Protein name | Brain acid soluble protein 1 |
|---|
| UniProt accession | P80723 |
|---|
| Gene | BASP1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 227 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (126)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.38
- inflammatory bowel disease · score 0.36
- Back pain · score 0.33
- serum gamma-glutamyl transferase measurement · score 0.32
- genetic disorder · score 0.12
- head and neck squamous cell carcinoma · score 0.09
- melanoma · score 0.08
- acute myeloid leukemia · score 0.08
- body mass index · score 0.07
- gonorrhea · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P80723-F1 | alphafold | PREDICTED | 51.57 | — |
Amino-acid sequence (227 residues)
MGGKLSKKKK GYNVNDEKAK EKDKKAEGAA TEEEGTPKES EPQAAAEPAE AKEGKEKPDQ DAEGKAEEKE GEKDAAAAKE EAPKAEPEKT EGAAEAKAEP PKAPEQEQAA PGPAAGGEAP KAAEAAAAPA ESAAPAAGEE PSKEEGEPKK TEAPAAPAAQ ETKSDGAPAS DSKPGSSEAA PSSKETPAAT EAPSSTPKAQ GPAASAEEPK PVEAPAANSD QTVTVKE
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