Beta-defensin 103 (DEFB103A)

About Beta-defensin 103

Beta-defensin 103 (DEFB103A) is a protein from Homo sapiens identified by UniProt accession P81534, 67 residues long. MolForge cross-references it against 0 known binders and 19 disease associations.

Target properties

Protein name	Beta-defensin 103
UniProt accession	P81534
Gene	DEFB103A
Organism	Homo sapiens
Length	67 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (19)

Diseases linked to this target (Open Targets).

neuroticism measurement · score 0.05
ghosal hematodiaphyseal dysplasia · score 0.04
melorheostosis · score 0.03
12q14 microdeletion syndrome · score 0.03
bleeding disorder, platelet-type, 24 · score 0.03
platelet-type bleeding disorder 15 · score 0.03
osteomesopyknosis · score 0.03
pyknoachondrogenesis · score 0.03
emotional symptom measurement · score 0.03
psoriasis · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P81534-F1	alphafold	PREDICTED	84.86	—

Amino-acid sequence (67 residues)

MRIHYLLFAL LFLFLVPVPG HGGIINTLQK YYCRVRGGRC AVLSCLPKEE QIGKCSTRGR KCCRRKK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards