About Small ribosomal subunit protein mS25
Small ribosomal subunit protein mS25 (MRPS25) is a protein
from Homo sapiens identified by UniProt accession
P82663, 173 residues long.
MolForge cross-references it against 0 known binders and
24 disease associations.
Target properties
| Protein name | Small ribosomal subunit protein mS25 |
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| UniProt accession | P82663 |
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| Gene | MRPS25 |
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| Organism | Homo sapiens |
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| Length | 173 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (24)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.46
- combined oxidative phosphorylation deficiency 50 · score 0.45
- IGF-1 measurement · score 0.21
- bone density · score 0.12
- urate measurement · score 0.12
- 22q11.2 deletion syndrome · score 0.05
- hypoparathyroidism, familial isolated, 2 · score 0.04
- Primary hypomagnesemia with secondary hypocalcemia · score 0.04
- Familial isolated hypoparathyroidism · score 0.04
- hyperinsulinism due to INSR deficiency · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P82663-F1 | alphafold | PREDICTED | 92.46 | — |
Amino-acid sequence (173 residues)
MPMKGRFPIR RTLQYLSQGN VVFKDSVKVM TVNYNTHGEL GEGARKFVFF NIPQIQYKNP WVQIMMFKNM TPSPFLRFYL DSGEQVLVDV ETKSNKEIME HIRKILGKNE ETLREEEEEK KQLSHPANFG PRKYCLRECI CEVEGQVPCP SLVPLPKEMR GKYKAALKAD AQD
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