Small ribosomal subunit protein mS35 (MRPS35)

About Small ribosomal subunit protein mS35

Small ribosomal subunit protein mS35 (MRPS35) is a protein from Homo sapiens identified by UniProt accession P82673, 323 residues long. MolForge cross-references it against 0 known binders and 27 disease associations.

Target properties

Protein name	Small ribosomal subunit protein mS35
UniProt accession	P82673
Gene	MRPS35
Organism	Homo sapiens
Length	323 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (27)

Diseases linked to this target (Open Targets).

FEV/FVC ratio · score 0.30
type 2 diabetes mellitus · score 0.26
mitochondrial DNA measurement · score 0.21
neurodegenerative disease · score 0.19
osteoarthritis, hip · score 0.05
osteoarthritis · score 0.05
cortical surface area measurement · score 0.05
vital capacity · score 0.04
self reported educational attainment · score 0.04
cortical thickness · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P82673-F1	alphafold	PREDICTED	84.78	—

Amino-acid sequence (323 residues)

MAAAALPAWL SLQSRARTLR AFSTAVYSAT PVPTPSLPER TPGNERPPRR KALPPRTEKM AVDQDWPSVY PVAAPFKPSA VPLPVRMGYP VKKGVPMAKE GNLELLKIPN FLHLTPVAIK KHCEALKDFC TEWPAALDSD EKCEKHFPIE IDSTDYVSSG PSVRNPRARV VVLRVKLSSL NLDDHAKKKL IKLVGERYCK TTDVLTIKTD RCPLRRQNYD YAVYLLTVLY HESWNTEEWE KSKTEADMEE YIWENSSSER NILETLLQMK AAEKNMEINK EELLGTKEIE EYKKSVVSLK NEEENENSIS QYKESVKRLL NVT

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards