Small ribosomal subunit protein uS5m (MRPS5)

About Small ribosomal subunit protein uS5m

Small ribosomal subunit protein uS5m (MRPS5) is a protein from Homo sapiens identified by UniProt accession P82675, 430 residues long. MolForge cross-references it against 0 known binders and 28 disease associations.

Target properties

Protein name	Small ribosomal subunit protein uS5m
UniProt accession	P82675
Gene	MRPS5
Organism	Homo sapiens
Length	430 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (28)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.46
leprosy · score 0.06
Parkinson disease · score 0.03
cardiac hypertrophy · score 0.02
gonorrhea · score 0.02
infect · score 0.01
infection · score 0.01
myocardial infarction · score 0.01
Ataxia-telangiectasia · score 0.01
anxiety · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P82675-F1	alphafold	PREDICTED	81.89	—

Amino-acid sequence (430 residues)

MATAVRAVGC LPVLCSGTAG HLLGRQCSLN TLPAASILAW KSVLGNGHLS SLGTRDTHPY ASLSRALQTQ CCISSPSHLM SQQYRPYSFF TKLTADELWK GALAETGAGA KKGRGKRTKK KKRKDLNRGQ IIGEGRYGFL WPGLNVPLMK NGAVQTIAQR SKEEQEKVEA DMIQQREEWD RKKKMKVKRE RGWSGNSWGG ISLGPPDPGP CGETYEDFDT RILEVRNVFT MTAKEGRKKS IRVLVAVGNG KGAAGFSIGK ATDRMDAFRK AKNRAVHHLH YIERYEDHTI FHDISLRFKR THIKMKKQPK GYGLRCHRAI ITICRLIGIK DMYAKVSGSI NMLSLTQGLF RGLSRQETHQ QLADKKGLHV VEIREECGPL PIVVASPRGP LRKDPEPEDE VPDVKLDWED VKTAQGMKRS VWSNLKRAAT

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards