About Small ribosomal subunit protein uS11m
Small ribosomal subunit protein uS11m (MRPS11) is a protein
from Homo sapiens identified by UniProt accession
P82912, 194 residues long.
MolForge cross-references it against 0 known binders and
21 disease associations.
Target properties
| Protein name | Small ribosomal subunit protein uS11m |
|---|
| UniProt accession | P82912 |
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| Gene | MRPS11 |
|---|
| Organism | Homo sapiens |
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| Length | 194 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (21)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.54
- major depressive disorder · score 0.11
- protein measurement · score 0.08
- age at menarche · score 0.06
- age at first facial hair · score 0.05
- gut microbiome measurement · score 0.03
- unipolar depression · score 0.02
- testosterone measurement · score 0.02
- chronic obstructive pulmonary disease · score 0.01
- polycystic ovary syndrome · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P82912-F1 | alphafold | PREDICTED | 82.91 | — |
Amino-acid sequence (194 residues)
MQAVRNAGSR FLRSWTWPQT AGRVVARTPA GTICTGARQL QDAAAKQKVE QNAAPSHTKF SIYPPIPGEE SSLRWAGKKF EEIPIAHIKA SHNNTQIQVV SASNEPLAFA SCGTEGFRNA KKGTGIAAQT AGIAAAARAK QKGVIHIRVV VKGLGPGRLS AMHGLIMGGL EVISITDNTP IPHNGCRPRK ARKL
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