About Small ribosomal subunit protein uS15m
Small ribosomal subunit protein uS15m (MRPS15) is a protein
from Homo sapiens identified by UniProt accession
P82914, 257 residues long.
MolForge cross-references it against 0 known binders and
41 disease associations.
Target properties
| Protein name | Small ribosomal subunit protein uS15m |
|---|
| UniProt accession | P82914 |
|---|
| Gene | MRPS15 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 257 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (41)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.54
- Alzheimer disease · score 0.32
- Parkinson disease · score 0.31
- lysosomal storage disease · score 0.31
- multiple sclerosis · score 0.31
- age at menopause · score 0.14
- neutrophil count · score 0.10
- protein measurement · score 0.08
- neuroticism measurement · score 0.07
- mathematical ability · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P82914-F1 | alphafold | PREDICTED | 78.42 | — |
Amino-acid sequence (257 residues)
MLRVAWRTLS LIRTRAVTQV LVPGLPGGGS AKFPFNQWGL QPRSLLLQAA RGYVVRKPAQ SRLDDDPPPS TLLKDYQNVP GIEKVDDVVK RLLSLEMANK KEMLKIKQEQ FMKKIVANPE DTRSLEARII ALSVKIRSYE EHLEKHRKDK AHKRYLLMSI DQRKKMLKNL RNTNYDVFEK ICWGLGIEYT FPPLYYRRAH RRFVTKKALC IRVFQETQKL KKRRRALKAA AAAQKQAKRR NPDSPAKAIP KTLKDSQ
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