Small ribosomal subunit protein bS21m (MRPS21)

About Small ribosomal subunit protein bS21m

Small ribosomal subunit protein bS21m (MRPS21) is a protein from Homo sapiens identified by UniProt accession P82921, 87 residues long. MolForge cross-references it against 0 known binders and 58 disease associations.

Target properties

Protein name	Small ribosomal subunit protein bS21m
UniProt accession	P82921
Gene	MRPS21
Organism	Homo sapiens
Length	87 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (58)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.48
forced expiratory volume · score 0.13
Red cell distribution width · score 0.12
glomerular filtration rate · score 0.11
asthma · score 0.10
neutrophil count · score 0.10
circadian rhythm · score 0.10
multisite chronic pain · score 0.10
peak expiratory flow · score 0.09
basophil count · score 0.09

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P82921-F1	alphafold	PREDICTED	96.30	—

Amino-acid sequence (87 residues)

MAKHLKFIAR TVMVQEGNVE SAYRTLNRIL TMDGLIEDIK HRRYYEKPCC RRQRESYERC RRIYNMEMAR KINFLMRKNR ADPWQGC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards