Small ribosomal subunit protein bS6m (MRPS6)

About Small ribosomal subunit protein bS6m

Small ribosomal subunit protein bS6m (MRPS6) is a protein from Homo sapiens identified by UniProt accession P82932, 125 residues long. MolForge cross-references it against 0 known binders and 57 disease associations.

Target properties

Protein name	Small ribosomal subunit protein bS6m
UniProt accession	P82932
Gene	MRPS6
Organism	Homo sapiens
Length	125 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (57)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.48
erythrocyte count · score 0.32
coronary artery disease · score 0.22
myocardial infarction · score 0.22
angina pectoris · score 0.21
hemoglobin measurement · score 0.21
hematocrit · score 0.21
heel bone mineral density · score 0.21
pulse pressure measurement · score 0.21
diastolic blood pressure · score 0.20

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P82932-F1	alphafold	PREDICTED	92.68	—

Amino-acid sequence (125 residues)

MPRYELALIL KAMQRPETAA TLKRTIEALM DRGAIVRDLE NLGERALPYR ISAHSQQHNR GGYFLVDFYA PTAAVESMVE HLSRDIDVIR GNIVKHPLTQ ELKECEGIVP VPLAEKLYST KKRKK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards