Large ribosomal subunit protein eL24 (RPL24)

About Large ribosomal subunit protein eL24

Large ribosomal subunit protein eL24 (RPL24) is a protein from Homo sapiens identified by UniProt accession P83731, 157 residues long. MolForge cross-references it against 0 known binders and 188 disease associations.

Target properties

Protein name	Large ribosomal subunit protein eL24
UniProt accession	P83731
Gene	RPL24
Organism	Homo sapiens
Length	157 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (188)

Diseases linked to this target (Open Targets).

Duchenne muscular dystrophy · score 0.50
cystic fibrosis · score 0.50
influenza · score 0.46
Becker muscular dystrophy · score 0.29
qualitative or quantitative defects of dystrophin · score 0.26
body height · score 0.19
IGF-1 measurement · score 0.11
aniridia · score 0.09
diffuse large B-cell lymphoma · score 0.08
epilepsy · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P83731-F1	alphafold	PREDICTED	80.47	—

Amino-acid sequence (157 residues)

MKVELCSFSG YKIYPGHGRR YARTDGKVFQ FLNAKCESAF LSKRNPRQIN WTVLYRRKHK KGQSEEIQKK RTRRAVKFQR AITGASLADI MAKRNQKPEV RKAQREQAIR AAKEAKKAKQ ASKKTAMAAA KAPTKAAPKQ KIVKPVKVSA PRVGGKR

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards