Orexigenic neuropeptide QRFP (QRFP)

About Orexigenic neuropeptide QRFP

Orexigenic neuropeptide QRFP (QRFP) is a protein from Homo sapiens identified by UniProt accession P83859, 136 residues long. MolForge cross-references it against 0 known binders and 30 disease associations.

Target properties

Protein name	Orexigenic neuropeptide QRFP
UniProt accession	P83859
Gene	QRFP
Organism	Homo sapiens
Length	136 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (30)

Diseases linked to this target (Open Targets).

glioblastoma multiforme · score 0.26
cutaneous melanoma · score 0.18
squamous cell lung carcinoma · score 0.12
body mass index · score 0.11
type 2 diabetes mellitus · score 0.07
insomnia measurement · score 0.07
body height · score 0.07
body weight · score 0.07
lean body mass · score 0.06
hemoglobin measurement · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P83859-F1	alphafold	PREDICTED	57.76	—

Amino-acid sequence (136 residues)

MVRPYPLIYF LFLPLGACFP LLDRREPTDA MGGLGAGERW ADLAMGPRPH SVWGSSRWLR ASQPQALLVI ARGLQTSGRE HAGCRFRFGR QDEGSEATGF LPAAGEKTSG PLGNLAEELN GYSRKKGGFS FRFGRR

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards