Large ribosomal subunit protein eL42 (RPL36A)

About Large ribosomal subunit protein eL42

Large ribosomal subunit protein eL42 (RPL36A) is a protein from Homo sapiens identified by UniProt accession P83881, 106 residues long. MolForge cross-references it against 0 known binders and 26 disease associations.

Target properties

Protein name	Large ribosomal subunit protein eL42
UniProt accession	P83881
Gene	RPL36A
Organism	Homo sapiens
Length	106 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (26)

Diseases linked to this target (Open Targets).

Duchenne muscular dystrophy · score 0.50
cystic fibrosis · score 0.50
influenza · score 0.46
Becker muscular dystrophy · score 0.29
qualitative or quantitative defects of dystrophin · score 0.26
pancreatic adenocarcinoma · score 0.22
glioblastoma multiforme · score 0.15
aniridia · score 0.09
diffuse large B-cell lymphoma · score 0.08
epilepsy · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P83881-F1	alphafold	PREDICTED	94.34	—

Amino-acid sequence (106 residues)

MVNVPKTRRT FCKKCGKHQP HKVTQYKKGK DSLYAQGKRR YDRKQSGYGG QTKPIFRKKA KTTKKIVLRL ECVEPNCRSK RMLAIKRCKH FELGGDKKRK GQVIQF

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards