About Chromobox protein homolog 1
Chromobox protein homolog 1 (CBX1) is a protein
from Homo sapiens identified by UniProt accession
P83916, 185 residues long.
MolForge cross-references it against 0 known binders and
188 disease associations.
Target properties
| Protein name | Chromobox protein homolog 1 |
|---|
| UniProt accession | P83916 |
|---|
| Gene | CBX1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 185 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (188)
Diseases linked to this target (Open Targets).
- viral disease · score 0.46
- neurodegenerative disease · score 0.37
- endometrial carcinoma · score 0.32
- body height · score 0.24
- triglyceride measurement · score 0.20
- Neurodevelopmental disorder · score 0.19
- lean body mass · score 0.13
- aspartate aminotransferase measurement · score 0.13
- body mass index · score 0.12
- myeloid white cell count · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P83916-F1 | alphafold | PREDICTED | 76.13 | — |
Amino-acid sequence (185 residues)
MGKKQNKKKV EEVLEEEEEE YVVEKVLDRR VVKGKVEYLL KWKGFSDEDN TWEPEENLDC PDLIAEFLQS QKTAHETDKS EGGKRKADSD SEDKGEESKP KKKKEESEKP RGFARGLEPE RIIGATDSSG ELMFLMKWKN SDEADLVPAK EANVKCPQVV ISFYEERLTW HSYPSEDDDK KDDKN
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