Enhancer of rudimentary homolog (ERH)

About Enhancer of rudimentary homolog

Enhancer of rudimentary homolog (ERH) is a protein from Homo sapiens identified by UniProt accession P84090, 104 residues long. MolForge cross-references it against 0 known binders and 43 disease associations.

Target properties

Protein name	Enhancer of rudimentary homolog
UniProt accession	P84090
Gene	ERH
Organism	Homo sapiens
Length	104 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (43)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.49
neutrophil count · score 0.17
neutrophil percentage of leukocytes · score 0.17
leukocyte count · score 0.16
myeloid white cell count · score 0.14
lymphocyte percentage of leukocytes · score 0.13
granulocyte percentage of myeloid white cells · score 0.13
sum of basophil and neutrophil counts · score 0.11
sum of neutrophil and eosinophil counts · score 0.11
neoplasm · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P84090-F1	alphafold	PREDICTED	95.93	—

Amino-acid sequence (104 residues)

MSHTILLVQP TKRPEGRTYA DYESVNECME GVCKMYEEHL KRMNPNSPSI TYDISQLFDF IDDLADLSCL VYRADTQTYQ PYNKDWIKEK IYVLLRRQAQ QAGK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards