Rho-related GTP-binding protein RhoG (RHOG)

About Rho-related GTP-binding protein RhoG

Rho-related GTP-binding protein RhoG (RHOG) is a protein from Homo sapiens identified by UniProt accession P84095, 191 residues long. MolForge cross-references it against 0 known binders and 124 disease associations.

Target properties

Protein name	Rho-related GTP-binding protein RhoG
UniProt accession	P84095
Gene	RHOG
Organism	Homo sapiens
Length	191 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P84095-F1	alphafold	PREDICTED	93.91	—

Amino-acid sequence (191 residues)

MQSIKCVVVG DGAVGKTCLL ICYTTNAFPK EYIPTVFDNY SAQSAVDGRT VNLNLWDTAG QEEYDRLRTL SYPQTNVFVI CFSIASPPSY ENVRHKWHPE VCHHCPDVPI LLVGTKKDLR AQPDTLRRLK EQGQAPITPQ QGQALAKQIH AVRYLECSAL QQDGVKEVFA EAVRAVLNPT PIKRGRSCIL L

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards