About Large ribosomal subunit protein eL19
Large ribosomal subunit protein eL19 (RPL19) is a protein
from Homo sapiens identified by UniProt accession
P84098, 196 residues long.
MolForge cross-references it against 0 known binders and
63 disease associations.
Target properties
| Protein name | Large ribosomal subunit protein eL19 |
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| UniProt accession | P84098 |
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| Gene | RPL19 |
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| Organism | Homo sapiens |
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| Length | 196 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
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Disease associations (63)
Diseases linked to this target (Open Targets).
- Duchenne muscular dystrophy · score 0.50
- cystic fibrosis · score 0.50
- influenza · score 0.46
- Becker muscular dystrophy · score 0.29
- clear cell renal carcinoma · score 0.27
- endometrial cancer · score 0.27
- qualitative or quantitative defects of dystrophin · score 0.26
- aniridia · score 0.09
- diffuse large B-cell lymphoma · score 0.08
- hepatocellular carcinoma · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P84098-F1 | alphafold | PREDICTED | 94.74 | — |
Amino-acid sequence (196 residues)
MSMLRLQKRL ASSVLRCGKK KVWLDPNETN EIANANSRQQ IRKLIKDGLI IRKPVTVHSR ARCRKNTLAR RKGRHMGIGK RKGTANARMP EKVTWMRRMR ILRRLLRRYR ESKKIDRHMY HSLYLKVKGN VFKNKRILME HIHKLKADKA RKKLLADQAE ARRSKTKEAR KRREERLQAK KEEIIKTLSK EEETKK
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