About SKI family transcriptional corepressor 1
SKI family transcriptional corepressor 1 (SKOR1) is a protein
from Homo sapiens identified by UniProt accession
P84550, 965 residues long.
MolForge cross-references it against 0 known binders and
63 disease associations.
Target properties
| Protein name | SKI family transcriptional corepressor 1 |
|---|
| UniProt accession | P84550 |
|---|
| Gene | SKOR1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 965 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (63)
Diseases linked to this target (Open Targets).
- body mass index · score 0.47
- body fat percentage · score 0.39
- lean body mass · score 0.30
- physical activity measurement · score 0.30
- fat body mass · score 0.27
- age at menarche · score 0.27
- obesity · score 0.27
- type 2 diabetes mellitus · score 0.26
- body weight · score 0.25
- smoking behavior · score 0.25
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P84550-F1 | alphafold | PREDICTED | 54.07 | — |
Amino-acid sequence (965 residues)
MALLCGLGQV TLRIWVSLPS QSENGIGFLA ARAFLRSGGM EALTTQLGPG REGSSSPNSK QELQPYSGSS ALKPNQVGET SLYGVPIVSL VIDGQERLCL AQISNTLLKN YSYNEIHNRR VALGITCVQC TPVQLEILRR AGAMPISSRR CGMITKREAE RLCKSFLGEH KPPKLPENFA FDVVHECAWG SRGSFIPARY NSSRAKCIKC GYCSMYFSPN KFIFHSHRTP DAKYTQPDAA NFNSWRRHLK LSDKSATDEL SHAWEDVKAM FNGGTRKRTF SLQGGGGGGA NGGSGGQGKG GAGGGGGGGP GCGAEMAPGP PPHKSLRCGE DEAAGPPGPP PPHPQRGLGL ATGASGPAGP GGPGGGAGVR SYPVIPVPSK GFGLLQKLPP PLFPHPYGFP TAFGLCPKKD DPVLGAGEPK GGPGTGSGGG GAGTGGGAGG PGASHLPPGA GAGPGGGAMF WGHQPSGAAK DAAAVAAAAA AATVYPTFPM FWPAAGSLPV PSYPAAQSQA KAVAAAVAAA AAAAAAAAGS GAPEPLDGAE PAKESGLGAE ERCPSALSRG PLDEDGTDEA LPPPLAPLPP PPPPPARKGS YVSAFRPVVK DTESIAKLYG SAREAYGAGP ARGPGPGAGS GGYVSPDFLS EGSSSYNSAS PDVDTADEPE VDVESNRFPD DEDAQEETEP SAPSAGGGPD GEQPTGPPSA TSSGADGPAN SPDGGSPRPR RRLGPPPAGR PAFGDLAAED LVRRPERSPP SGGGGYELRE PCGPLGGPAP AKVFAPERDE HVKSAAVALG PAASYVCTPE AHEPDKEDNH SPADDLETRK SYPDQRSISQ PSPANTDRGE DGLTLDVTGT HLVEKDIENL AREELQKLLL EQMELRKKLE REFQSLKDNF QDQMKRELAY REEMVQQLQI VRDTLCNELD QERKARYAIQ QKLKEAHDAL HHFSCKMLTP RHCTGNCSFK PPLLP
Explore SKI family transcriptional corepressor 1 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets