About Zinc finger X-linked protein ZXDA
Zinc finger X-linked protein ZXDA (ZXDA) is a protein
from Homo sapiens identified by UniProt accession
P98168, 799 residues long.
MolForge cross-references it against 0 known binders and
9 disease associations.
Target properties
| Protein name | Zinc finger X-linked protein ZXDA |
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| UniProt accession | P98168 |
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| Gene | ZXDA |
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| Organism | Homo sapiens |
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| Length | 799 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (9)
Diseases linked to this target (Open Targets).
- Fraser syndrome · score 0.11
- androgenetic alopecia · score 0.08
- balding measurement · score 0.04
- type 2 diabetes mellitus · score 0.04
- Ataxia-telangiectasia · score 0.04
- platelet count · score 0.03
- complication · score 0.02
- colorectal adenocarcinoma · score 0.00
- cancer · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P98168-F1 | alphafold | PREDICTED | 54.06 | — |
Amino-acid sequence (799 residues)
MEIPKLLPAR GTLQGGGGGG IPAGGGRVHR GPDSPAGQVP TRRLLLPRGP QDGGPGRRRE EASTASRGPG PSLFAPRPHQ PSGGGDDFFL VLLDPVGGDV ETAGSGQAAG PVLREEAKAG PGLQGDESGA NPAGCSAQGP HCLSAVPTPA PISAPGPAAA FAGTVTIHNQ DLLLRFENGV LTLATPPPHA WEPGAAPAQQ PRCLIAPQAG FPQAAHPGDC PELRSDLLLA EPAEPAPAPA PQEEAEGLAA ALGPRGLLGS GPGVVLYLCP EALCGQTFAK KHQLKMHLLT HSSSQGQRPF KCPLGGCGWT FTTSYKLKRH LQSHDKLRPF GCPAEGCGKS FTTVYNLKAH MKGHEQENSF KCEVCEESFP TQAKLGAHQR SHFEPERPYQ CAFSGCKKTF ITVSALFSHN RAHFREQELF SCSFPGCSKQ YDKACRLKIH LRSHTGERPF LCDFDGCGWN FTSMSKLLRH KRKHDDDRRF MCPVEGCGKS FTRAEHLKGH SITHLGTKPF VCPVAGCCAR FSARSSLYIH SKKHLQDVDT WKSRCPISSC NKLFTSKHSM KTHMVKRHKV GQDLLAQLEA ANSLTPSSEL TSQRQNDLSD AEIVSLFSDV PDSTSAALLD TALVNSGILT IDVASVSSTL AGHLPANNNN SVGQAVDPPS LMATSDPPQS LDTSLFFGTA ATGFQQSSLN MDEVSSVSVG PLGSLDSLAM KNSSPEPQAL TPSSKLTVDT DTLTPSSTLC ENSVSELLTP AKAEWSVHPN SDFFGQEGET QFGFPNAAGN HGSQKERNLI TVTGSSFLV
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