Cytochrome c (CYCS)

About Cytochrome c

Cytochrome c (CYCS) is a protein from Homo sapiens identified by UniProt accession P99999, 105 residues long. MolForge cross-references it against 0 known binders and 542 disease associations.

Target properties

Protein name	Cytochrome c
UniProt accession	P99999
Gene	CYCS
Organism	Homo sapiens
Length	105 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Approved drugs hitting this target (1)

DrugCentral-linked approved drugs that act on this protein.

Disease associations (542)

Diseases linked to this target (Open Targets).

thrombocytopenia 4 · score 0.71
neurodegenerative disease · score 0.56
Thrombocytopenia · score 0.39
autosomal thrombocytopenia with normal platelets · score 0.37
hereditary nonpolyposis colon cancer · score 0.34
GNE myopathy · score 0.34
low grade glioma · score 0.28
response to vaccine · score 0.27
lymphocyte count · score 0.27
Abnormal bleeding · score 0.26

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P99999-F1	alphafold	PREDICTED	97.93	—

Amino-acid sequence (105 residues)

MGDVEKGKKI FIMKCSQCHT VEKGGKHKTG PNLHGLFGRK TGQAPGYSYT AANKNKGIIW GEDTLMEYLE NPKKYIPGTK MIFVGIKKKE ERADLIAYLK KATNE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards