About Homeobox protein Hox-C5
Homeobox protein Hox-C5 (HOXC5) is a protein
from Homo sapiens identified by UniProt accession
Q00444, 222 residues long.
MolForge cross-references it against 0 known binders and
76 disease associations.
Target properties
| Protein name | Homeobox protein Hox-C5 |
|---|
| UniProt accession | Q00444 |
|---|
| Gene | HOXC5 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 222 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (76)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.54
- platelet count · score 0.23
- platelet crit · score 0.19
- BMI-adjusted waist circumference · score 0.19
- systolic blood pressure · score 0.19
- BMI-adjusted waist-hip ratio · score 0.18
- smoking behavior · score 0.18
- body fat percentage · score 0.18
- sex hormone-binding globulin measurement · score 0.18
- alcohol drinking · score 0.17
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q00444-F1 | alphafold | PREDICTED | 65.95 | — |
Amino-acid sequence (222 residues)
MSSYVANSFY KQSPNIPAYN MQTCGNYGSA SEVQASRYCY GGLDLSITFP PPAPSNSLHG VDMAANPRAH PDRPACSAAA APGHAPGRDE AAPLNPGMYS QKAARPALEE RAKSSGEIKE EQAQTGQPAG LSQPPAPPQI YPWMTKLHMS HETDGKRSRT SYTRYQTLEL EKEFHFNRYL TRRRRIEIAN NLCLNERQIK IWFQNRRMKW KKDSKMKSKE AL
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