Pregnancy-specific beta-1-glycoprotein 9 (PSG9)

About Pregnancy-specific beta-1-glycoprotein 9

Pregnancy-specific beta-1-glycoprotein 9 (PSG9) is a protein from Homo sapiens identified by UniProt accession Q00887, 426 residues long. MolForge cross-references it against 0 known binders and 45 disease associations.

Target properties

Protein name	Pregnancy-specific beta-1-glycoprotein 9
UniProt accession	Q00887
Gene	PSG9
Organism	Homo sapiens
Length	426 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (45)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.45
blood protein measurement · score 0.32
blood phosphate measurement · score 0.30
glioblastoma multiforme · score 0.18
thyroid gland adenocarcinoma · score 0.16
head and neck squamous cell carcinoma · score 0.11
low grade glioma · score 0.10
obesity due to melanocortin 4 receptor deficiency · score 0.06
LIPE-related familial partial lipodystrophy · score 0.04
obesity due to leptin receptor gene deficiency · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q00887-F1	alphafold	PREDICTED	87.05	—

Amino-acid sequence (426 residues)

MGPLPAPSCT QRITWKGLLL TASLLNFWNP PTTAEVTIEA QPPKVSEGKD VLLLVHNLPQ NLPGYFWYKG EMTDLYHYII SYIVDGKIII YGPAYSGRET VYSNASLLIQ NVTRKDAGTY TLHIIKRGDE TREEIRHFTF TLYLETPKPY ISSSNLNPRE AMEAVRLICD PETLDASYLW WMNGQSLPVT HRLQLSKTNR TLYLFGVTKY IAGPYECEIR NPVSASRSDP VTLNLLPKLP IPYITINNLN PRENKDVLAF TCEPKSENYT YIWWLNGQSL PVSPGVKRPI ENRILILPSV TRNETGPYQC EIRDRYGGLR SNPVILNVLY GPDLPRIYPS FTYYRSGENL DLSCFTESNP PAEYFWTING KFQQSGQKLF IPQITRNHSG LYACSVHNSA TGKEISKSMT VKVSGPCHGD LTESQS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards