Protein BEX3 (BEX3)

About Protein BEX3

Protein BEX3 (BEX3) is a protein from Homo sapiens identified by UniProt accession Q00994, 111 residues long. MolForge cross-references it against 0 known binders and 69 disease associations.

Target properties

Protein name	Protein BEX3
UniProt accession	Q00994
Gene	BEX3
Organism	Homo sapiens
Length	111 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (69)

Diseases linked to this target (Open Targets).

glioblastoma multiforme · score 0.08
lung adenocarcinoma · score 0.07
neuroblastoma · score 0.07
Spinal cord injury · score 0.06
Familial ocular anterior segment mesenchymal dysgenesis · score 0.05
kidney disease · score 0.03
congenital primary aphakia · score 0.03
cancer · score 0.03
megalocornea · score 0.03
Megalocornea · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q00994-F1	alphafold	PREDICTED	64.62	—

Amino-acid sequence (111 residues)

MANIHQENEE MEQPMQNGEE DRPLGGGEGH QPAGNRRGQA RRLAPNFRWA IPNRQINDGM GGDGDDMEIF MEEMREIRRK LRELQLRNCL RILMGELSNH HDHHDEFCLM P

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards