About Interleukin-9 receptor
Interleukin-9 receptor (IL9R) is a protein
from Homo sapiens identified by UniProt accession
Q01113, 521 residues long.
MolForge cross-references it against 0 known binders and
73 disease associations.
Target properties
| Protein name | Interleukin-9 receptor |
|---|
| UniProt accession | Q01113 |
|---|
| Gene | IL9R |
|---|
| Organism | Homo sapiens |
|---|
| Length | 521 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (73)
Diseases linked to this target (Open Targets).
- autoimmune disease · score 0.05
- common variable immunodeficiency · score 0.04
- inborn error of immunity · score 0.04
- infect · score 0.04
- infection · score 0.04
- experimental autoimmune encephalomyelitis · score 0.04
- severe combined immunodeficiency due to CARD11 deficiency · score 0.04
- autoimmune lymphoproliferative syndrome · score 0.04
- severe combined immunodeficiency due to CTPS1 deficiency · score 0.04
- reticular dysgenesis · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q01113-F1 | alphafold | PREDICTED | 63.12 | — |
Amino-acid sequence (521 residues)
MGLGRCIWEG WTLESEALRR DMGTWLLACI CICTCVCLGV SVTGEGQGPR SRTFTCLTNN ILRIDCHWSA PELGQGSSPW LLFTSNQAPG GTHKCILRGS ECTVVLPPEA VLVPSDNFTI TFHHCMSGRE QVSLVDPEYL PRRHVKLDPP SDLQSNISSG HCILTWSISP ALEPMTTLLS YELAFKKQEE AWEQAQHRDH IVGVTWLILE AFELDPGFIH EARLRVQMAT LEDDVVEEER YTGQWSEWSQ PVCFQAPQRQ GPLIPPWGWP GNTLVAVSIF LLLTGPTYLL FKLSPRVKRI FYQNVPSPAM FFQPLYSVHN GNFQTWMGAH GAGVLLSQDC AGTPQGALEP CVQEATALLT CGPARPWKSV ALEEEQEGPG TRLPGNLSSE DVLPAGCTEW RVQTLAYLPQ EDWAPTSLTR PAPPDSEGSR SSSSSSSSNN NNYCALGCYG GWHLSALPGN TQSSGPIPAL ACGLSCDHQG LETQQGVAWV LAGHCQRPGL HEDLQGMLLP SVLSKARSWT F
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