About Protein Dr1
Protein Dr1 (DR1) is a protein
from Homo sapiens identified by UniProt accession
Q01658, 176 residues long.
MolForge cross-references it against 0 known binders and
142 disease associations.
Target properties
| Protein name | Protein Dr1 |
|---|
| UniProt accession | Q01658 |
|---|
| Gene | DR1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 176 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (142)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.52
- high density lipoprotein cholesterol measurement · score 0.33
- urate measurement · score 0.27
- apolipoprotein A 1 measurement · score 0.26
- serum alanine aminotransferase measurement · score 0.24
- alkaline phosphatase measurement · score 0.23
- alcohol drinking · score 0.22
- mean corpuscular hemoglobin concentration · score 0.22
- triglyceride measurement · score 0.21
- C-reactive protein measurement · score 0.20
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q01658-F1 | alphafold | PREDICTED | 87.27 | — |
Amino-acid sequence (176 residues)
MASSSGNDDD LTIPRAAINK MIKETLPNVR VANDARELVV NCCTEFIHLI SSEANEICNK SEKKTISPEH VIQALESLGF GSYISEVKEV LQECKTVALK RRKASSRLEN LGIPEEELLR QQQELFAKAR QQQAELAQQE WLQMQQAAQQ AQLAAASASA SNQAGSSQDE EDDDDI
Explore Protein Dr1 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets