About Flavin-containing monooxygenase 1
Flavin-containing monooxygenase 1 (FMO1) is a protein
from Homo sapiens identified by UniProt accession
Q01740, 532 residues long.
MolForge cross-references it against 0 known binders and
51 disease associations.
Target properties
| Protein name | Flavin-containing monooxygenase 1 |
|---|
| UniProt accession | Q01740 |
|---|
| Gene | FMO1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 532 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (51)
Diseases linked to this target (Open Targets).
- neutrophil count · score 0.29
- myeloid white cell count · score 0.26
- cutaneous melanoma · score 0.18
- diffuse plaque measurement · score 0.08
- urinary metabolite measurement · score 0.04
- Kidney Oncocytoma · score 0.03
- 3-hydroxy-1-methylpropylmercapturic acid measurement · score 0.03
- gonorrhea · score 0.03
- non-alcoholic fatty liver disease · score 0.02
- chromophobe renal cell carcinoma · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q01740-F1 | alphafold | PREDICTED | 94.44 | — |
Amino-acid sequence (532 residues)
MAKRVAIVGA GVSGLASIKC CLEEGLEPTC FERSDDLGGL WRFTEHVEEG RASLYKSVVS NSCKEMSCYS DFPFPEDYPN YVPNSQFLEY LKMYANHFDL LKHIQFKTKV CSVTKCSDSA VSGQWEVVTM HEEKQESAIF DAVMVCTGFL TNPYLPLDSF PGINAFKGQY FHSRQYKHPD IFKDKRVLVI GMGNSGTDIA VEASHLAEKV FLSTTGGGWV ISRIFDSGYP WDMVFMTRFQ NMLRNSLPTP IVTWLMERKI NNWLNHANYG LIPEDRTQLK EFVLNDELPG RIITGKVFIR PSIKEVKENS VIFNNTSKEE PIDIIVFATG YTFAFPFLDE SVVKVEDGQA SLYKYIFPAH LQKPTLAIIG LIKPLGSMIP TGETQARWAV RVLKGVNKLP PPSVMIEEIN ARKENKPSWF GLCYCKALQS DYITYIDELL TYINAKPNLF SMLLTDPHLA LTVFFGPCSP YQFRLTGPGK WEGARNAIMT QWDRTFKVIK ARVVQESPSP FESFLKVFSF LALLVAIFLI FL
Explore Flavin-containing monooxygenase 1 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets