About Transgelin
Transgelin (TAGLN) is a protein
from Homo sapiens identified by UniProt accession
Q01995, 201 residues long.
MolForge cross-references it against 0 known binders and
297 disease associations.
Target properties
| Protein name | Transgelin |
|---|
| UniProt accession | Q01995 |
|---|
| Gene | TAGLN |
|---|
| Organism | Homo sapiens |
|---|
| Length | 201 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (297)
Diseases linked to this target (Open Targets).
- triglyceride measurement · score 0.24
- systolic blood pressure · score 0.21
- monocyte count · score 0.20
- blood protein measurement · score 0.17
- body mass index · score 0.16
- cerebrospinal fluid biomarker measurement · score 0.13
- appendicular lean mass · score 0.13
- Calcium channel blocker use measurement · score 0.13
- neoplasm · score 0.11
- esophageal squamous cell carcinoma · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q01995-F1 | alphafold | PREDICTED | 88.16 | — |
Amino-acid sequence (201 residues)
MANKGPSYGM SREVQSKIEK KYDEELEERL VEWIIVQCGP DVGRPDRGRL GFQVWLKNGV ILSKLVNSLY PDGSKPVKVP ENPPSMVFKQ MEQVAQFLKA AEDYGVIKTD MFQTVDLFEG KDMAAVQRTL MALGSLAVTK NDGHYRGDPN WFMKKAQEHK REFTESQLQE GKHVIGLQMG SNRGASQAGM TGYGRPRQII S
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