About A-kinase anchor protein 17A
A-kinase anchor protein 17A (AKAP17A) is a protein
from Homo sapiens identified by UniProt accession
Q02040, 695 residues long.
MolForge cross-references it against 0 known binders and
19 disease associations.
Target properties
| Protein name | A-kinase anchor protein 17A |
|---|
| UniProt accession | Q02040 |
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| Gene | AKAP17A |
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| Organism | Homo sapiens |
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| Length | 695 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (19)
Diseases linked to this target (Open Targets).
- ovarian carcinoma · score 0.01
- ulcerative colitis · score 0.01
- Tourette syndrome · score 0.01
- obsessive-compulsive disorder · score 0.01
- diffuse large B-cell lymphoma · score 0.00
- respiratory distress syndrome in premature infants · score 0.00
- lymphoproliferative syndrome · score 0.00
- hematopoietic and lymphoid system neoplasm · score 0.00
- neoplasm · score 0.00
- Hodgkins lymphoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q02040-F1 | alphafold | PREDICTED | 69.48 | — |
Amino-acid sequence (695 residues)
MAAATIVHDT SEAVELCPAY GLYLKPITKM TISVALPQLK QPGKSISNWE VMERLKGMVQ NHQFSTLRIS KSTMDFIRFE GEVENKSLVK SFLACLDGKT IKLSGFSDIL KVRAAEFKID FPTRHDWDSF FRDAKDMNET LPGERPDTIH LEGLPCKWFA LKESGSEKPS EDVLVKVFEK FGEIRNVDIP MLDPYREEMT GRNFHTFSFG GHLNFEAYVQ YREYMGFIQA MSALRGMKLM YKGEDGKAVA CNIKVSFDST KHLSDASIKK RQLERQKLQE LEQQREEQKR REKEAEERQR AEERKQKELE ELERERKREE KLRKREQKQR DRELRRNQKK LEKLQAEEQK QLQEKIKLEE RKLLLAQRNL QSIRLIAELL SRAKAVKLRE QEQKEEKLRL QQQEERRRLQ EAELRRVEEE KERALGLQRK ERELRERLLS ILLSKKPDDS HTHDELGVAH ADLLQPVLDI LQTVSSGCVS ATTLHPLGGQ PPAGAPKESP AHPEADGAPK SVNGSVAEEA PCKEVQSSCR VVPEDGSPEK RCPGGVLSCI PDNNQQPKGI PACEQNVSRK DTRSEQDKCN REPSKGRGRA TGDGLADRHK RERSRARRAS SREDGRPRKE RRPHKKHAYK DDSPRRRSTS PDHTRSRRSH SKDRHRRERS RERRGSASRK HSRHRRRSER SRSRSPSRHR STWNR
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