Myosin light chain 5 (MYL5)

About Myosin light chain 5

Myosin light chain 5 (MYL5) is a protein from Homo sapiens identified by UniProt accession Q02045, 173 residues long. MolForge cross-references it against 0 known binders and 49 disease associations.

Target properties

Protein name	Myosin light chain 5
UniProt accession	Q02045
Gene	MYL5
Organism	Homo sapiens
Length	173 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (49)

Diseases linked to this target (Open Targets).

retinitis pigmentosa · score 0.38
neurodegenerative disease · score 0.32
breast adenocarcinoma · score 0.18
congenital stationary night blindness · score 0.15
multiple sclerosis · score 0.14
Alzheimer disease · score 0.14
Parkinson disease · score 0.14
lysosomal storage disease · score 0.14
eyelid disease · score 0.09
cancer · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q02045-F1	alphafold	PREDICTED	83.96	—

Amino-acid sequence (173 residues)

MASRKTKKKE GGALRAQRAS SNVFSNFEQT QIQEFKEAFT LMDQNRDGFI DKEDLKDTYA SLGKTNVKDD ELDAMLKEAS GPINFTMFLN LFGEKLSGTD AEETILNAFK MLDPDGKGKI NKEYIKRLLM SQADKMTAEE VDQMFQFASI DVAGNLDYKA LSYVITHGEE KEE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards