About Myocyte-specific enhancer factor 2A
Myocyte-specific enhancer factor 2A (MEF2A) is a protein
from Homo sapiens identified by UniProt accession
Q02078, 507 residues long.
MolForge cross-references it against 0 known binders and
243 disease associations.
Target properties
| Protein name | Myocyte-specific enhancer factor 2A |
|---|
| UniProt accession | Q02078 |
|---|
| Gene | MEF2A |
|---|
| Organism | Homo sapiens |
|---|
| Length | 507 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (243)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.55
- coronary artery disease · score 0.48
- myocardial infarction · score 0.46
- systolic blood pressure · score 0.40
- basophil percentage of leukocytes · score 0.39
- vitamin D measurement · score 0.39
- coronary artery disease, autosomal dominant 2 · score 0.36
- arterial stiffness measurement · score 0.34
- basophil count · score 0.32
- mean arterial pressure · score 0.31
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q02078-F1 | alphafold | PREDICTED | 54.71 | — |
Amino-acid sequence (507 residues)
MGRKKIQITR IMDERNRQVT FTKRKFGLMK KAYELSVLCD CEIALIIFNS SNKLFQYAST DMDKVLLKYT EYNEPHESRT NSDIVEALNK KEHRGCDSPD PDTSYVLTPH TEEKYKKINE EFDNMMRNHK IAPGLPPQNF SMSVTVPVTS PNALSYTNPG SSLVSPSLAA SSTLTDSSML SPPQTTLHRN VSPGAPQRPP STGNAGGMLS TTDLTVPNGA GSSPVGNGFV NSRASPNLIG ATGANSLGKV MPTKSPPPPG GGNLGMNSRK PDLRVVIPPS SKGMMPPLSE EEELELNTQR ISSSQATQPL ATPVVSVTTP SLPPQGLVYS AMPTAYNTDY SLTSADLSAL QGFNSPGMLS LGQVSAWQQH HLGQAALSSL VAGGQLSQGS NLSINTNQNI SIKSEPISPP RDRMTPSGFQ QQQQQQQQQQ PPPPPQPQPQ PPQPQPRQEM GRSPVDSLSS SSSSYDGSDR EDPRGDFHSP IVLGRPPNTE DRESPSVKRM RMDAWVT
Explore Myocyte-specific enhancer factor 2A with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets