About Ammonium transporter Rh type A
Ammonium transporter Rh type A (RHAG) is a protein
from Homo sapiens identified by UniProt accession
Q02094, 409 residues long.
MolForge cross-references it against 0 known binders and
128 disease associations.
Target properties
| Protein name | Ammonium transporter Rh type A |
| UniProt accession | Q02094 |
| Gene | RHAG |
| Organism | Homo sapiens |
| Length | 409 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (128)
Diseases linked to this target (Open Targets).
- Rh deficiency syndrome · score 0.79
- overhydrated hereditary stomatocytosis · score 0.69
- reticulocyte count · score 0.59
- reticulocyte measurement · score 0.59
- HbA1c measurement · score 0.59
- mean corpuscular volume · score 0.59
- mean reticulocyte volume · score 0.58
- mean corpuscular hemoglobin concentration · score 0.56
- hematological measurement · score 0.46
- bilirubin measurement · score 0.40
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-Q02094-F1 | alphafold | PREDICTED | 95.62 | — |
Amino-acid sequence (409 residues)
MRFTFPLMAI VLEIAMIVLF GLFVEYETDQ TVLEQLNITK PTDMGIFFEL YPLFQDVHVM IFVGFGFLMT FLKKYGFSSV GINLLVAALG LQWGTIVQGI LQSQGQKFNI GIKNMINADF SAATVLISFG AVLGKTSPTQ MLIMTILEIV FFAHNEYLVS EIFKASDIGA SMTIHAFGAY FGLAVAGILY RSGLRKGHEN EESAYYSDLF AMIGTLFLWM FWPSFNSAIA EPGDKQCRAI VNTYFSLAAC VLTAFAFSSL VEHRGKLNMV HIQNATLAGG VAVGTCADMA IHPFGSMIIG SIAGMVSVLG YKFLTPLFTT KLRIHDTCGV HNLHGLPGVV GGLAGIVAVA MGASNTSMAM QAAALGSSIG TAVVGGLMTG LILKLPLWGQ PSDQNCYDDS VYWKVPKTR
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