Plasminogen-like protein B (PLGLB1)

About Plasminogen-like protein B

Plasminogen-like protein B (PLGLB1) is a protein from Homo sapiens identified by UniProt accession Q02325, 96 residues long. MolForge cross-references it against 0 known binders and 13 disease associations.

Target properties

Protein name	Plasminogen-like protein B
UniProt accession	Q02325
Gene	PLGLB1
Organism	Homo sapiens
Length	96 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (13)

Diseases linked to this target (Open Targets).

mitochondrial heteroplasmy measurement · score 0.17
keratinocyte carcinoma · score 0.07
hair color · score 0.07
basal cell carcinoma · score 0.07
COVID-19 · score 0.03
hepatocellular carcinoma · score 0.01
Crohn's disease · score 0.01
neoplasm · score 0.00
infect · score 0.00
infection · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q02325-F1	alphafold	PREDICTED	91.26	—

Amino-acid sequence (96 residues)

MEHKEVVLLL LLFLKSGQGE PLDDYVNTQG PSLFSVTKKQ LGAGSREECA AKCEEDKEFT CRAFQYHSKE QQCVIMAENR KSSIIIRMRD AVLFEK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards